Components for Antimicrobial Formulations
Solvents, surfactants, chelants and polymers can play an important role in creating effective antimicrobial formulations. The removal of soils from surfaces is often the first step in this process.
Surfactants will lower the surface tension and assist in the wetting and spreading of the active.
Solvents aid in the dispersion and dissolution of soils which helps apply the disinfectant to the surface.
Chelants help to control divalent cations to help remove tough stains like soap scum and hard water and keep surfactants more soluble, improving performance.
Polymers act as dispersants and inhibit scale and soil redeposition, which enables cleaning without residue.
Food-contact surface sanitizing solutions
Dow products can be used in accordance with: EPA 40 CFR 180.940 Active and Inert Ingredients for Use in Antimicrobial Formulations (Food-contact surface sanitizing solutions).
- The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-contact surfaces in public eating places, dairy processing equipment, and food-processing equipment and utensils.
- The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Dairy processing equipment, and food-processing equipment and utensils.
- The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food processing equipment and utensils.
40 CFR 180.950 Tolerance exemptions for minimal risk active and inert ingredients.
40 CFR 180.960 Polymers; exemptions from the requirement of a tolerance.
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Solvent | Structure | CAS# | EPA status | Limitation |
Butyl CELLOSOLVE™ Solvent | Ethylene glycol monobutyl ether | 111-76-2 | 180.940c | None |
CARBITOL™ Solvent | Diethylene glycol ethyl ether | 111-90-0 | 180.940c | None |
n-Butanol* | Alcohol | 71-36-3 | 180.940a | When ready for use, the end-use concentration is not to exceed 100 ppm |
Propionic acid | Oxo acid | 79-09-4 | 180.940a | When ready for use, the end-use concentration is not to exceed 100 ppm |
Propionic acid | Oxo acid | 79-09-4 | 180.940b,c | When ready for use, the end-use concentration is not to exceed 297 ppm |
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Solvent | Structure | CAS# | EPA status | Limitation |
ECOSURF™ EH-3, EH-6, EH-9, EH-9 (90%), EH-14 (90%) Surfactant** | 2-Ethyl hexanol EO-PO nonionic surfactant | 64366-70-7 | 180.940a | None |
ECOSURF™ SA-4, SA-7, SA-9, SA-15 Surfactant** | Seed oil surfactant | 68937-66-6, 69227-22-1 | 180.940a | None |
Polyglycol EP-436 | EO-PO nonionic low foam surfactant | 9003-11-6 | 180.940a, 180.960 | None |
Polyglycol P 2000*, P-3000*, P-4000* | Polypropylene Glycol | 25322-69-4 | 180.960 | None |
TERGITOL™ 15-S-3,15-S-5, 15-S-7, 15-S-9, 15-S-12,15-S-12 (90%), 15-S-15, 15-S-20, 15-S-20 (80%), 15-S-30, 15-S-40, 15-S-40 (70%) Surfactant | Secondary alcohol ethoxylate surfactant | 84133-50-6 | 180.940a | None |
TERGITOL™ L-61, L-62, L-64, L-81, L-101, HB-5100 Surfactant | EO-PO nonionic low foam surfactant | 9003-11-6 | 180.940a 180.960 | None |
TERGITOL™ MinFoam 1X and MinFoam 2X Surfactant | EO-PO nonionic low foam surfactant | 68439-51-0 | 180.940a | None |
TERGITOL™ NP-9, NP-9.5, N-10, NP-11, NP-12, NP-13 Surfactant | Nonylphenol ethoxylates | 127087-87-0 | 180.940a | None |
TERGITOL™ TMN-3, TMN-6 (90%), TMN-10 (90%), TMN-100X (90%) Surfactant | Branched secondary alcohol ethoxylates | 60828-78-6 | 180.940a | None |
TERGITOL™ XD, XH, XJ Surfactant | EO-PO nonionic low foam surfactant | 9038-95-3 | 180.940a | None |
TERGITOL™ XDLW Surfactant | Mixed surfactant | 9038-95-3, 84133-50-6 | 180.940a | None |
TRITON™ APG (CG-50, BG-10, CG-110) Surfactant | Alkyl polyglucosides | 68515-73-1 | 180.940a | None |
TRITON™ DF-16 Surfactant | EO-PO nonionic low foam surfactant | 68603-25-8 | 180.940a | None |
TRITON™ GR-5M Surfactant | Sulfosuccinate | 577-11-7, 67-63-0 | 180.940c | None |
TRITON™ HW-1000 Surfactant | Secondary alcohol ethoxylate | 60828-78-6 | 180.940a | None |
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Solvent | Structure | CAS# | EPA status | Limitation |
VERSENE™ 100 Chelating Agent | Chelant | 64-02-8 | 180.940a | None |
VERSENE™ 100LN Chelating Agent | Chelant | 64-02-8 | 180.940a | None |
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Solvent | Structure | CAS# | EPA status | Limitation |
ACUSOL™ 445N, 445 ND Polymers | Polymers | 68479-09-4 | 40 CFR 180.960 | None |
CELLOSIZE™ Hydroxyethyl Cellulose QP-15000-H Europe | Polymers | 9004-62-0 | 40 CFR 180.950 | None |
CELLOSIZE™ Hydroxyethyl Cellulose QP-52000-H Europe | Polymers | 9004-62-0 | 40 CFR 180.950 | None |
*Commodity inert
**ECOSURF™ is sold under trade name TERGITOL™ in Canada and Japan.
Nonfood surface sanitizing solutions
Dow surfactants, solvents, chelants, and polymers can be used in antimicrobial formulations where there is no food contact. Applications may include bathroom cleaners, hard surface cleaners, cleaning wipes, etc. In addition, all food use inert ingredients noted above are also permitted for nonfood use applications where there is no food contact. For surfaces that may come in contact with food, a potable water, rinse is required.
*Commodity inerts
EPA has developed a list of inert ingredients it has designated as commodity inert ingredients. Registrants and applicants completing the Confidential Statement of Formula (CSF) Form (EPA Form 8570-4) will no longer need to list the commodity inert ingredient suppliers.
To learn more, please visit: https://www.epa.gov/pesticide-registration/commodity-inert-ingredients
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Surfactant | CAS# | Clearance |
Butyl CARBITOL™ Solvent | 112-34-5 | Nonfood use |
Butyl CELLOSOLVE™ Acetate | 112-07-2 | Nonfood use |
Diisopropanolamine, LFG 85 | 110-97-4 | Nonfood use |
DOWANOL™ PM Glycol Ether | 107-98-2 | Nonfood use |
DOWANOL™ DPM Glycol Ether | 34590-94-8 | Nonfood use |
DOWANOL™ TPM Glycol Ether | 25498-49-1 | Nonfood use |
DOWANOL™ DPnP Glycol Ether | 29911-27-1 | Nonfood use |
DOWANOL™ TPnB Glycol Ether | 29911-28-2 | Nonfood use |
DOWANOL™ PPh Glycol Ether | 770-35-4 | Nonfood use |
DOWANOL™ EPH Glycol Ether | 122-99-6 | Nonfood use |
2-Ethyl-hexanol* | 104-76-7 | Nonfood use |
2 Ethylhexoic acid | 149-57-5 | Nonfood use |
Hexyl CELLOSOLVE™ Solvent | 112-25-4 | Nonfood use |
Isobutanol* | 78-83-1 | Nonfood use |
Isobutyl acetate | 110-19-0 | Nonfood use |
Isopropanol* | 67-63-0 | Nonfood use |
Isopropyl acetate | 108-21-4 | Nonfood use |
Methyl CARBITOL™ Solvent | 111-77-3 | Nonfood use |
n-Butanol* | 71-36-3 | When ready for use, the end-use concentration is not to exceed 100 ppm |
n-Butyl acetate | 123-86-4 | Nonfood use |
n-Propanol* | 71-23-8 | Nonfood use |
n-Propyl acetate | 109-60-4 | Nonfood use |
Primary amyl acetate mixed isomers | 628-63-7, 624-41-9 | Nonfood use |
Triethanolamine 99% LFG 85* | 102-71-6 | Nonfood use |
Trimethylnonanol | 123-17-1 | Nonfood use |
UCAR™ Ester EEP | 763-69-9 | Nonfood use |
Valeric acid | 109-52-4 | Nonfood use |
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Surfactant | CAS# | Clearance |
DOWFAX™ 2A1, 3B2, C10L, 8390 Surfactant | 119345-04-9, 65143-89-7, 70191-76-3, 36445-71-3 | Nonfood use |
Polyglycol PT 250, 700, 3000, 4800 | 9082-00-2 | Nonfood use |
Polyglycol P-425*, P-600*, 1000TB*, P 1200* | 25322-69-4 | Nonfood use |
TERGITOL™ NP-4, NP-6, NP-7, NP-8, NP-30 (70%), NP-40 (70%), NP-50 (70%) Surfactant | 127087-87-0 | Nonfood use |
TRITON™ APG (CG-425, CG-600, CG-650) Surfactant | 68515-73-1, 110615-47-9 | Nonfood use |
TRITON™ X-15, X-35, X-45, X-100, X-102 and X-114, X-165 (70%), X-305 (70%), X-405 (70%), X-705 (70%) Surfactant | 9036-19-5 | Nonfood use |
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Surfactant | CAS# | Clearance |
VERSENE™ 220 Crystals Chelating Agent | 13235-36-4 | Nonfood use |
VERSENE™ K4EDTA Chelating Agent | 5964-35-2 | Nonfood use |
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Surfactant | CAS# | Clearance |
ACUSOL™ 445 N, 445 ND Polymers | 68479-09-4 | Nonfood use |
ACUSOL™ 460N Polymer | Proprietary | Nonfood use |
ACUSOL™ 880 Polymer | Proprietary | Nonfood use |
ACUSOL™ Millennium Rheology Modifier | Proprietary | Nonfood use |
ACUSOL™ PRO Hard Surface Polymer | Proprietary | Nonfood use |
*Commodity inert
For more information, please refer to the EPA Inert site: https://www.epa.gov/pesticide-registration/inert-ingredients-overview-and-guidance.
Product stewardship
Dow has a fundamental concern for all who make, distribute, and use its products, and for the environment in which we live. This concern is the basis for our product stewardship philosophy by which we assess the safety, health, and environmental information on our products and then take appropriate steps to protect employee and public health and our environment. The success of our product stewardship program rests with each and every individual involved with Dow products - from the initial concept and research, to manufacture, use, sale, disposal, and recycle of each product.
Customer notice
Dow strongly encourages its customers to review both their manufacturing processes and their applications of Dow products from the standpoint of human health and environmental quality to ensure that Dow products are not used in ways for which they are not intended or tested. Dow personnel are available to answer your questions and to provide reasonable technical support. Dow product literature, including safety data sheets, should be consulted prior to use of Dow products. Current safety data sheets are available from Dow.
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