Close up of plastic tub filled with various cleaning supplies

Components for Antimicrobial Formulations

Solvents, surfactants, chelants and polymers can play an important role in creating effective antimicrobial formulations. The removal of soils from surfaces is often the first step in this process.

Surfactants will lower the surface tension and assist in the wetting and spreading of the active. 

Solvents aid in the dispersion and dissolution of soils which helps apply the disinfectant to the surface.

Chelants help to control divalent cations to help remove tough stains like soap scum and hard water and keep surfactants more soluble, improving performance.

Polymers act as dispersants and inhibit scale and soil redeposition, which enables cleaning without residue.

Food-contact surface sanitizing solutions

Dow products can be used in accordance with: EPA 40 CFR 180.940 Active and Inert Ingredients for Use in Antimicrobial Formulations (Food-contact surface sanitizing solutions).

  1. The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-contact surfaces in public eating places, dairy processing equipment, and food-processing equipment and utensils.
  2. The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Dairy processing equipment, and food-processing equipment and utensils.
  3. The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food processing equipment and utensils.


40 CFR 180.950 Tolerance exemptions for minimal risk active and inert ingredients.

40 CFR 180.960 Polymers; exemptions from the requirement of a tolerance.

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SolventStructureCAS#EPA statusLimitation
Butyl CELLOSOLVE™ Solvent Ethylene glycol monobutyl ether111-76-2180.940cNone
CARBITOL™ SolventDiethylene glycol ethyl ether111-90-0180.940cNone
n-Butanol*Alcohol71-36-3180.940aWhen ready for use, the end-use concentration is not to exceed 100 ppm
Propionic acidOxo acid79-09-4180.940aWhen ready for use, the end-use concentration is not to exceed 100 ppm
Propionic acidOxo acid79-09-4180.940b,cWhen ready for use, the end-use concentration is not to exceed 297 ppm

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SolventStructureCAS#EPA statusLimitation
ECOSURF™ EH-3, EH-6, EH-9, EH-9 (90%), 
EH-14 (90%) Surfactant** 
2-Ethyl hexanol EO-PO nonionic surfactant64366-70-7180.940aNone
ECOSURF™ SA-4, SA-7, SA-9, SA-15 Surfactant**Seed oil surfactant68937-66-6, 69227-22-1 180.940aNone
Polyglycol EP-436EO-PO nonionic low foam surfactant 9003-11-6180.940a, 180.960None
Polyglycol P 2000*, P-3000*, P-4000*Polypropylene Glycol25322-69-4180.960None
TERGITOL™ 15-S-3,15-S-5, 15-S-7, 15-S-9, 15-S-12,15-S-12 (90%), 15-S-15, 15-S-20, 15-S-20 (80%), 15-S-30, 15-S-40, 15-S-40 (70%) SurfactantSecondary alcohol ethoxylate surfactant84133-50-6180.940aNone
TERGITOL™ L-61, L-62, L-64, L-81, L-101, HB-5100 SurfactantEO-PO nonionic low foam surfactant9003-11-6180.940a 180.960None
TERGITOL™ MinFoam 1X and MinFoam 2X SurfactantEO-PO nonionic low foam surfactant68439-51-0180.940aNone
TERGITOL™ NP-9, NP-9.5, N-10, NP-11, NP-12, NP-13 SurfactantNonylphenol ethoxylates127087-87-0180.940aNone
TERGITOL™ TMN-3, TMN-6 (90%), TMN-10 (90%), TMN-100X (90%) SurfactantBranched secondary alcohol ethoxylates60828-78-6180.940aNone
TERGITOL™ XD, XH, XJ SurfactantEO-PO nonionic low foam surfactant9038-95-3180.940aNone
TERGITOL™ XDLW SurfactantMixed surfactant9038-95-3, 84133-50-6180.940aNone
TRITON™ APG (CG-50, BG-10, CG-110) SurfactantAlkyl polyglucosides68515-73-1180.940aNone
TRITON™ DF-16 SurfactantEO-PO nonionic low foam surfactant68603-25-8180.940aNone
TRITON™ GR-5M SurfactantSulfosuccinate577-11-7, 67-63-0180.940cNone
TRITON™ HW-1000 SurfactantSecondary alcohol ethoxylate60828-78-6180.940aNone

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SolventStructureCAS#EPA statusLimitation
VERSENE™ 100 Chelating AgentChelant64-02-8180.940aNone
VERSENE™ 100LN Chelating AgentChelant64-02-8180.940aNone

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SolventStructureCAS#EPA statusLimitation
ACUSOL™ 445N, 445 ND PolymersPolymers68479-09-440 CFR 180.960None
CELLOSIZE™ Hydroxyethyl Cellulose QP-15000-H EuropePolymers9004-62-040 CFR 180.950None
CELLOSIZE™ Hydroxyethyl Cellulose QP-52000-H EuropePolymers9004-62-040 CFR 180.950None

*Commodity inert

**ECOSURF™ is sold under trade name TERGITOL™ in Canada and Japan.

Nonfood surface sanitizing solutions

Dow surfactants, solvents, chelants, and polymers can be used in antimicrobial formulations where there is no food contact. Applications may include bathroom cleaners, hard surface cleaners, cleaning wipes, etc. In addition, all food use inert ingredients noted above are also permitted for nonfood use applications where there is no food contact. For surfaces that may come in contact with food, a potable water, rinse is required.

*Commodity inerts
EPA has developed a list of inert ingredients it has designated as commodity inert ingredients. Registrants and applicants completing the Confidential Statement of Formula (CSF) Form (EPA Form 8570-4) will no longer need to list the commodity inert ingredient suppliers. 

To learn more, please visit: https://www.epa.gov/pesticide-registration/commodity-inert-ingredients

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SurfactantCAS#Clearance
Butyl CARBITOL™ Solvent112-34-5Nonfood use
Butyl CELLOSOLVE™ Acetate112-07-2Nonfood use
Diisopropanolamine, LFG 85110-97-4Nonfood use
DOWANOL™ PM Glycol Ether107-98-2Nonfood use
DOWANOL™ DPM Glycol Ether34590-94-8Nonfood use
DOWANOL™ TPM Glycol Ether25498-49-1Nonfood use
DOWANOL™ DPnP Glycol Ether 29911-27-1 Nonfood use
DOWANOL™ TPnB Glycol Ether29911-28-2Nonfood use
DOWANOL™ PPh Glycol Ether770-35-4Nonfood use
DOWANOL™ EPH Glycol Ether122-99-6Nonfood use
2-Ethyl-hexanol*104-76-7Nonfood use
2 Ethylhexoic acid149-57-5Nonfood use
Hexyl CELLOSOLVE™ Solvent112-25-4Nonfood use
Isobutanol*78-83-1Nonfood use
Isobutyl acetate110-19-0Nonfood use
Isopropanol*67-63-0Nonfood use
Isopropyl acetate108-21-4Nonfood use
Methyl CARBITOL™ Solvent111-77-3Nonfood use
n-Butanol*71-36-3When ready for use, the end-use concentration is not to exceed 100 ppm
n-Butyl acetate123-86-4Nonfood use
n-Propanol*71-23-8Nonfood use
n-Propyl acetate109-60-4Nonfood use
Primary amyl acetate mixed isomers628-63-7, 624-41-9Nonfood use
Triethanolamine 99% LFG 85*102-71-6Nonfood use
Trimethylnonanol123-17-1Nonfood use
UCAR™ Ester EEP763-69-9Nonfood use
Valeric acid109-52-4Nonfood use

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SurfactantCAS#Clearance
DOWFAX™ 2A1, 3B2, C10L, 8390 Surfactant119345-04-9, 65143-89-7, 70191-76-3, 36445-71-3Nonfood use
Polyglycol PT 250, 700, 3000, 48009082-00-2Nonfood use
Polyglycol P-425*, P-600*, 1000TB*, P 1200*25322-69-4Nonfood use
TERGITOL™ NP-4, NP-6, NP-7, NP-8, NP-30 (70%), NP-40 (70%), NP-50 (70%) Surfactant127087-87-0Nonfood use
TRITON™ APG (CG-425, CG-600, CG-650) Surfactant68515-73-1, 110615-47-9Nonfood use
TRITON™ X-15, X-35, X-45, X-100, X-102 and X-114, X-165 (70%), X-305 (70%), X-405 (70%), X-705 (70%) Surfactant9036-19-5Nonfood use

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SurfactantCAS#Clearance
VERSENE™ 220 Crystals Chelating Agent13235-36-4Nonfood use
VERSENE™ K4EDTA Chelating Agent5964-35-2Nonfood use

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SurfactantCAS#Clearance
ACUSOL™ 445 N, 445 ND Polymers68479-09-4 Nonfood use
ACUSOL™ 460N PolymerProprietaryNonfood use
ACUSOL™ 880 PolymerProprietaryNonfood use
ACUSOL™ Millennium Rheology ModifierProprietaryNonfood use
ACUSOL™ PRO Hard Surface PolymerProprietaryNonfood use

*Commodity inert

For more information, please refer to the EPA Inert site: https://www.epa.gov/pesticide-registration/inert-ingredients-overview-and-guidance.

Product stewardship

Dow has a fundamental concern for all who make, distribute, and use its products, and for the environment in which we live. This concern is the basis for our product stewardship philosophy by which we assess the safety, health, and environmental information on our products and then take appropriate steps to protect employee and public health and our environment. The success of our product stewardship program rests with each and every individual involved with Dow products - from the initial concept and research, to manufacture, use, sale, disposal, and recycle of each product. 

Customer notice

Dow strongly encourages its customers to review both their manufacturing processes and their applications of Dow products from the standpoint of human health and environmental quality to ensure that Dow products are not used in ways for which they are not intended or tested. Dow personnel are available to answer your questions and to provide reasonable technical support. Dow product literature, including safety data sheets, should be consulted prior to use of Dow products. Current safety data sheets are available from Dow. 

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